Thanks for reaching out about this. A few things to double check:
Make sure you’re using a valid refresh token (refresh tokens are valid once, and you need to make sure you’re using the latest refresh token that was returned when you originally requested an access_token)
Ensure that the Client ID:Client Secret are base 64 encoded and match the app you retrieved the access_token for originally
Try reauthorizing the app and starting with a fresh access_token and refresh_token pair