If you changed the production URL of the app you will want to reinstall the app.
However, if you have submitted your application and are looking to change a setting on the production app it will require that you re-submit the application with the new production redirect URL.
However, in the case of re-submitting the process is much quicker as they just have to address the incremental updates.
I hope that helps! If not, please follow up with the support ticket that was created.